Anti-A antibody would attack blood cells that contain A antigen. Group B: The surface of the red blood cells contains B antigen, and the plasma has anti-A antibody. Anti-B antibody would attack blood cells that contain B antigen. Group A: The surface of the red blood cells contains A antigen, and the plasma has anti-B antibody. They use the ABO system alongside the RhD antigen status to determine which blood type or types will match for a safe red blood cell transfusion. The ABO blood group system classifies blood types according to the different types of antigens in the red blood cells and antibodies in the plasma. This can cause a severe and possibly life-threatening reaction. This is why it is essential to match blood types when a person needs a transfusion.Īccording to the American Red Cross, If a person receives red blood cells with antigens that are not already present in their system, their body will reject and attack the new red blood cells. These antibodies will target an antigen if they consider it a foreign object. Scientists use two types of antigens to classify blood types:Īntigens and antibodies play a role in the immune system’s defense mechanism. detecting unwanted cells that could cause illness.maintaining the structure of red blood cells.transporting other molecules into and out of the cell.The antigens in blood have various functions, including: The types and features of antigens can vary between individuals, due to small genetic differences. The blood group will depend on which antigens are on the surface of the red blood cells.Īntigens are molecules. plasma, which is a yellowish liquid that contains proteins and salts.white blood cells, which play a crucial role in the immune system.red blood cells, which carry oxygen around the body.

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